Asian Oncology Research Journal https://journalaorj.com/index.php/AORJ <p style="text-align: justify;"><strong>Asian Oncology Research Journal</strong>&nbsp;aims to publish&nbsp;high-quality&nbsp;papers (<a href="/index.php/AORJ/general-guideline-for-authors">Click here for Types of paper</a>) in all areas of&nbsp;‘Cancer, Tumor&nbsp;and&nbsp;Oncology&nbsp;research’. By not excluding papers based on novelty, this journal facilitates the research and wishes to publish papers as long as they are technically correct and scientifically motivated. The journal also encourages the submission of useful reports of negative results. This is a quality controlled, OPEN peer-reviewed, open-access INTERNATIONAL journal.</p> en-US contact@journalaorj.com (Asian Oncology Research Journal) contact@journalaorj.com (Asian Oncology Research Journal) Thu, 01 Feb 2024 09:44:32 +0000 OJS 3.3.0.11 http://blogs.law.harvard.edu/tech/rss 60 Knowledge and Attitude of Pregnant Women Attending Antenatal Clinic at University College Hospital towards Causes and Methods of Prevention of Cervical Cancer https://journalaorj.com/index.php/AORJ/article/view/87 <p>Nigerian women of childbearing age who are sexually active are the at risk of cervical cancer (CC), since they may have been exposed to Human Papilloma virus. Majority of the women with invasive cervical cancer were never screened for this disease which is known to be a major cause of cancer deaths among women, especially in developing nations. Mortality and morbidity arising from non-communicable diseases like cancer have continued to pose threat to the life of women. Cervical cancer is one of the common cancers and is responsible for the death of many women. This study was therefore designed to investigate the knowledge of pregnant women attending antenatal clinic at University Teaching Hospital Ibadan about cervical cancer and their attitude towards its methods of prevention.</p> <p>A descriptive cross-sectional design was adopted and a total of one hundred and forty-seven (147) pregnant women were selected at the antenatal clinic at University Teaching Hospital Ibadan using a simple random sampling method. Self-structured questionnaire was used to collected the date from the respondents while descriptive statistics was used to analyze the data. Respondents’ ages ranged between 18 and 50 which is the average reproductive age of women, of which 80% had at least secondary school education while the remaining 20% had only primary school education.</p> <p>The study confirmed that most of the respondents had heard about cervical cancer screening and know where it can be done. While the awareness of cervical; cancer is high unfortunately, the perception that it can be treated is quite low. Knowledge, attitude and perception of women attending ante-natal clinic on cervical cancer screening often an important opportunity for comprehensive prevention and preventive strategies of the disease especially during the early stage if detected on time. Noteworthy is that majority of the respondents are aware of cervical cancer, however they are not aware of the vaccines that can help prevent it. Their knowledge of the relationship of cervical cancer is not accurate. Also, they don’t know that women should be checked every three years by health professionals for cervical cancer. Similarly, they do not have enough information about the different types of test that should be carried out for the detection of cervical cancer.</p> <p>Hence, there is a large gap between level of knowledge and attitude of pregnant women attending antenatal clinic at University Teaching Hospital Ibadan towards causes and methods of preventing cervical cancer. Efforts should be put in place to bridge this gap to reduce the incidence of women with cervical cancer.</p> Olanrewaju John Adedayo , Akinyele-Williams Titilope Felicia Copyright (c) 2024 Adedayo and Felicia; This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. https://journalaorj.com/index.php/AORJ/article/view/87 Thu, 25 Jan 2024 00:00:00 +0000 Evaluation of Clinical Response and Toxicities of Concurrent Weekly Cisplatin in Comparison to Weekly Paclitaxel with External Beam Radiotherapy in the Treatment of Locally Advanced Cervical Cancer (IIB-IVA) https://journalaorj.com/index.php/AORJ/article/view/88 <p>This quasi-experimental study was performed in the Department of Radiotherapy of Dhaka Medical College Hospital, Dhaka for one year period from July 2019 to June 2020. The aim of the study was to evaluate and compare tumor response and toxicities of weekly cisplatin and paclitaxel along with External Beam Radiotherapy in the treatment of locally advanced cervical cancer. Sixty previously untreated female patients with histologically proven locally advanced squamous cell carcinoma of cervix (stage IIB-IVA) were randomized into concurrent chemoradiation with weekly cisplatin and weekly paclitaxel group with thirty patients falling in each group. They were followed up for 3 months at the OPD. Treatment response and toxicities were assessed and compared between two groups. Majority of the patients in both groups were less than 50 years of age. The mean number of chemotherapy cycles was comparable with 90% and 80% of patients receiving 5 doses in arm A &amp; B respectively. Nausea &amp; vomiting were higher in cisplatin group. Diarrhea, allergic reaction, peripheral neuropathy &amp; neutropenia were more in paclitaxel group. There was a complete response rate of 63.3% in cisplatin group and 56.7% paclitaxel group. There were only 3 patients who discontinued treatment (1 in cisplatin group &amp; 2 in paclitaxel group) due to drug-related toxicities. This small prospective study shows that weekly paclitaxel was as effective as weekly cisplatin in concurrent chemoradiation for locally advanced carcinoma of cervix. So, paclitaxel can be used as an alternative to cisplatin in cisplatin contraindicated cases.</p> Nahid Naznin Rinky , Mukti Rani Datta , Dipok Saha , Sarker Md. Tanvir , Tannima Adhikary , Tanin Sultana , Mohammad Ashraf-Us-Zaman Mahmud , A. T. M. Shazzaeatur Rahaman , Mohammad Saiful Islam Pathan Copyright (c) 2024 Author(s). The licensee is the journal publisher. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0 ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. https://journalaorj.com/index.php/AORJ/article/view/88 Fri, 23 Feb 2024 00:00:00 +0000