Asian Oncology Research Journal 2020-10-05T07:23:24+00:00 Asian Oncology Research Journal Open Journal Systems <p style="text-align: justify;"><strong>Asian Oncology Research Journal</strong>&nbsp;aims to publish&nbsp;high-quality&nbsp;papers (<a href="/index.php/AORJ/general-guideline-for-authors">Click here for Types of paper</a>) in all areas of&nbsp;‘Cancer, Tumor&nbsp;and&nbsp;Oncology&nbsp;research’. This journal facilitates the research and wishes to publish papers as long as they are technically correct, scientifically motivated. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer-reviewed, open access INTERNATIONAL journal.</p> <p style="text-align: justify;">&nbsp;</p> Short Term Outcome of Sphincter Saving Procedure in Low Rectal Cancer 2020-08-08T13:10:07+00:00 Mohamed Salah Abdelhamid Tamer Mohamed El- Gaabary Ahmed Mohamed Rashad Amr Mohamed Ali Bekheet <p>Intersphincteric resection of low rectal tumors is a surgical technique extending rectal resection into the intersphincteric space. This procedure is performed by a synchronous abdominoperineal approach with mesorectal excision and excision of the entire or part of the internal sphincter.</p> <p><strong>Aim of the Work:</strong> Aim of the work is to evaluate the oncological and functional outcome of sphincter saving procedures.</p> <p><strong>Patients:</strong> 10 patients who meet the criteria of ISR possibility and candidates for sphincter saving procedures this study was conducted al Beni Suef University hospital between January 2019 and March 2020.</p> <p><strong>Methods:</strong> Total ISR involves complete excision of the internal sphincter. The cut line is at the intersphincteric groove. B. Subtotal ISR involves partial excision of the internal sphincter. The cut line is between the dentate line and the intersphincteric groove. C. Modified partial ISR the cut line is below the dentate line on one side of the tumor. On the opposite side of the tumor, the cut line is above the dentate line. D. Partial ISR the cut line is at or above the level of the dentate line.</p> <p><strong>Results</strong><strong>:</strong> Results showed that out of 10 patients underwent ISR, 6 patients were highly satisfied with Grade I continence according to Kirwan’s grade. While 4 patients were Grade II, i.e.: Incontinent to flatus. 30% rate of recurrence.</p> <p><strong>Conclusion:</strong> In low rectal cancer, the sphincter saving appears to have acceptable oncologic outcome. However, patients with sphincter saving have certainly demonstrated an indisputable faire functional outcome, in terms of stoma avoidance and adequate continence.</p> 2020-08-08T00:00:00+00:00 ##submission.copyrightStatement## An Interventional Study to Assess the Best Strategy and to Promote the Practice of Breast Self Examination among Nursing Staff in Bangalore 2020-09-02T08:00:21+00:00 Subi Ansari Priya T. Nandimath N. S. N. Rao <p><strong>Aims: </strong>The aim of this study was to assess the effects of different methods of instruction on nurses' Breast Self Examination (BSE) practice and to assess the influence of constructs of health belief model on practice of BSE among nurses.</p> <p><strong>Study Design</strong><strong>:</strong> Completely Randomized design.</p> <p><strong>Place and Duration of the Study</strong><strong>:</strong> A descriptive cross sectional study was conducted among the female nurses working in a tertiary care hospital in Bangalore for 2 years.</p> <p><strong>Materials and methods:</strong> A completely randomized study was conducted with a sample of 90 nurses, 30 each from Control Group, Lecture group, Video Group were included in the study. The study included pre-test; post-test and three month follow up of control group and two experimental groups (lecture and video). The control group was not given any intervention, the lecture group received intervention through a tailor made lecture session and video group received the intervention with a video on knowledge and practice of BSE.</p> <p><strong>Results: </strong>Both lecture and video methods of BSE instruction significantly increased the nurses' mean BSE effectiveness scores (F=23.878 and p= 0.000), supporting the first hypothesis. The group of nurses with the lecture and video group displayed the almost similar improvement in BSE technique with mean score at follow up. The mean score was almost same with lecture and video group. Hence both the methods of interventions were effective in improving the practice of BSE.</p> <p>The scores of health belief constructs among nurses who practiced BSE were significantly higher than the health belief scores of nurses who did not practice BSE, supporting second hypothesis. At follow up the Health Belief Model variables, perceived seriousness (p = 0.034) and perceived benefit (p = 0.037) were significant predictors of BSE practice and at pre-test perceived barriers (P=0.024) was significant predictor of BSE practice. This signifies that (Health Belief Model) theoretical framework is useful understanding beliefs attitudes and values for the preventive health behaviour.</p> <p><strong>Conclusion: </strong>Lecture and video can be used as best strategies to improve the effectiveness of BSE among the nurses. Nurse’s health belief constructs especially perceived seriousness and perceived benefits were significant predictors to influence nurses BSE.</p> 2020-09-02T00:00:00+00:00 ##submission.copyrightStatement## Protective Effect of Damiana (Turnera diffusa) against Growth of Ehrlich Ascites Carcinoma in Female Mice 2020-10-05T07:23:24+00:00 Afaf El- Atrsh Kholoud Al- Ashmouny Ehab Tousson <p><strong>Background and Objective:</strong> Ehrlich ascites carcinoma (EAC) is primarily derived from a murine mammary adenocarcinoma. It is a common tumor an undifferentiated carcinoma with high transplantable capability, no regression, rapid proliferation, shorter life span, 100% malignancy and also does not have tumor-specific transplantation antigen. The current study aim to study the protective role of damiana against Ehrlich ascites carcinoma (EAC) induced blood, liver and kidney damage in mice.</p> <p><strong>Materials and Methods</strong><strong>:</strong> A total of 75 female mice were divided into 5 groups the 1st group was control group, 2nd group was damiana group, 3rd group was EAC group, 4th group was pre-treated EAC with damiana, and 5th group was co-treated EAC with damiana.</p> <p><strong>Results:</strong> Current results revealed that; EAC induce significant increase in AST, ALT, ALP, urea, creatinine, potassium ions (K+), chloride ions (Cl-), cholesterol, triglyceride and low density lipoprotein-cholesterol (LDL) while EAC induce significant decrease in total proteins, albumin, sodium ion (Na+), calcium ion (Ca2+) and high density lipoprotein-cholesterol (HDL) as compared to control group.</p> <p><strong>Conclusion:</strong> Treatment of EAC with damiana as pre-treated or co-treated modeulates this parameters with best results for pretreatment than co-treatments. It could be concluded that; damiana has hepatic and renal protective effect against EAC induced changes in blood.</p> 2020-10-05T00:00:00+00:00 ##submission.copyrightStatement##