Radiological and Histopathological Diagnosis of Pulmonary Mass according to CT-Guided FNAC and Core Biopsy

Tariqul Islam *

Department of Radiology and Imaging, Sheikh Hasina National Institute of Burn and Plastic Surgery, Dhaka, Bangladesh.

Syed Mohammad Sajjad Jalal

Sheikh Hasina National, Institute of Burn and Plastic Surgery, Dhaka, Bangladesh.

Al Asma Ul Taslima

Sheikh Hasina National, Institute of Burn and Plastic Surgery, Dhaka, Bangladesh.

Asaduzzaman

Department of Histopathology, Sheikh Hasina National Institute of Burn and Plastic Surgery, Dhaka, Bangladesh.

Farhana Kamal Kumu

Sheikh Hasina National, Institute of Burn and Plastic Surgery, Dhaka, Bangladesh.

Mst. Nadira Parvin

Department of Epidemiology, Bangladesh University of Health Sciences (BUHS), Dhaka, Bangladesh.

*Author to whom correspondence should be addressed.


Abstract

Background: Computed Tomography (CT) guided core biopsy and Fine-needle aspiration cytology (FNAC) are crucial diagnostic procedures for swiftly assessing pulmonary masses. They play a pivotal role in expediting the diagnosis process of such lesions.

Aims: The primary objectives of this study were to evaluate the effectiveness of CT-guided core biopsy and FNAC in diagnosing pulmonary mass lesions and to compare their results with histopathological findings.

Methods: We conducted a prospective analysis of 45 patients who underwent CT-guided core biopsy and FNAC between June 2022 and August 2023. Subsequently, patients clinically indicated for further assessment underwent tru-cut biopsy.

Results: Among the 45 cases studied, the majority (60%) fell within the age group of 50-65 years, followed by 28.9% and 11.1% in the age groups of 15-45 and 65+, respectively. The mean age was 52.13±13.91 years. Gender distribution showed that 67% of the respondents were male, while 33% were female. Regarding diagnostic procedures, 51.1% underwent core biopsy, 44.4% underwent FNAC, and only 4.4% opted for tru-cut biopsy. Radiological diagnoses indicated that 42.2% of the respondents had neoplastic masses, 24.4% exhibited metastatic lesions, 15.6% displayed consolidation, and 2.2% were diagnosed with tumors, tuberculosis, or chronic obstructive pulmonary disease (COPD). Histopathological results demonstrated that 33.3% of the respondents had carcinoma, 24.4% tested negative for malignant cells, 22.2% showed fibrosis, and 8.9%, 6.7%, and 4.4% were diagnosed with inflammatory lesions, pulmonary tuberculosis, and pleural effusion, respectively.

Conclusion: CT-guided core biopsy and FNAC emerged as straightforward, accessible, and dependable techniques for expeditiously establishing a tissue diagnosis of pulmonary masses while presenting minimal complications.

Keywords: FNAC, radiological diagnosis, histopathological, pulmonary mass


How to Cite

Islam , T., Jalal , S. M. S., Taslima, A. A. U., Asaduzzaman, Kumu , F. K., & Parvin , M. N. (2023). Radiological and Histopathological Diagnosis of Pulmonary Mass according to CT-Guided FNAC and Core Biopsy. Asian Oncology Research Journal, 6(1), 105–110. Retrieved from https://journalaorj.com/index.php/AORJ/article/view/85

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