Use of DNA Methylation in Cancer Therapy
Ayoola Abimbola *
Department of Biomedical Engineering, University of Bridgeport, Bridgeport. CT., USA.
Christian Bach
Department of Biomedical Engineering, University of Bridgeport, Bridgeport. CT., USA.
*Author to whom correspondence should be addressed.
Abstract
The aim of this paper is the review the factors that determine cancer progression which would help in the treatment and diagnosis of the disease. Cancer is a leading life-threatening disease and despite the recent technological advancement, there is still a poor survival rate in cancer patients because of inadequate diagnosis and poor prognosis of cancer.
Keywords: Cancer, hypomethylation, hypermethylation, genes, tumor suppressor genes, epigenetic, receptor ligands, chemotherapy, DNA transferases, chromosomal arrangements, tumor suppressor, biomarker, hormone therapy, chromatin structure.