Thyroid Follicular Carcinoma with Distant Metastasis to the Calvaria
Asian Oncology Research Journal,
A case of thyroid follicular carcinoma with distant metastasis to the calvaria at initial presentation and its management in a resource-constrained environment.
A 69-year-old woman who presented with an anterior neck mass, scalp swelling and right eye proptosis and was diagnosed with thyroid follicular cancer with metastasis to the skull and right eye.
Thyroid cancer (TC) is the most common endocrine cancer worldwide, accounting for 567,000 cases and 41,071 deaths in 2018. The commonest type of TC is papillary thyroid cancer (75- 85%) followed by follicular thyroid cancer (10- 20%). Although distant metastasis of TC to the lung and bones are common, metastasis to the calvaria is less common and relatively few cases have been reported in the medical literature.
Metastasis of thyroid cancer (TC) to the calvaria and by extension to other infrequently reported areas is a relatively rare but possible complication of TC.
- Thyroid cancer
- follicular thyroid cancer
- distant metastasis
How to Cite
Bray F, Ferlay J, Soerjomataram I, Siegel R, Torre L, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians. 2018;68(6):394-424.
National cancer institute, SEER. Cancer of the Thyroid - Cancer Stat Facts [Internet]. SEER. 2017 [cited 27 November 2019]. Available:https://seer.cancer.gov/statfacts/html/thyro.html.
Oertel Y.C., Oertel J.E. Papillary Carcinoma.Thyroid Cancer. Springerlink. 2006;978-1-59259-995-0.
Ogbera A, Kuku S. Epidemiology of thyroid diseases in Africa. Indian Journal of Endocrinology and Metabolism. 2011;15(6):82.
Ukekwe F. Patterns of Thyroid Cancers in Southeastern Nigeria: A 15 Year Histopathologic Review (2000-2014). Journal of Clinical and Diagnostic Research. 2017 Aug; 11(8): EC16–EC19. DOI: 10.7860/JCDR/2017/26971.10418
EM D, Y T, RK G, EK W. Trends in Thyroid Malignancies in Accra Ghana: A Retrospective Histopathological Review in the Department of Pathology (1994-2013), Korle-Bu Teaching Hospital. Journal of Cancer science and Clinical Oncology. 2018;5(1).
Wang L, Palmer F, Nixon I, Thomas D, Patel S, Shaha A et al. Multi-Organ Distant Metastases Confer Worse Disease-Specific Survival in Differentiated Thyroid Cancer. Thyroid. 2014;24(11):1594-1599.
Farwell A. THYROID CANCER Survival prognosis in metastatic thyroid cancer [Internet]. Thyroid.org. 2015 [cited 18 November 2019]. Available from: https://www.thyroid.org/wp-content/uploads/publications/ctfp/volume8/issue4/ct_public_v84_11.pdf
Siegel R, Miller K, Jemal A. Cancer statistics, 2020. CA: A Cancer Journal for Clinicians. 2020;70(1):7-30.
Rahman G, Abdulkadir A, Olatoke S, Yusuf I, Braimoh K. Unusual cutaneous metastatic follicular thyroid carcinoma. Journal of Surgical Technique and Case Report. 2010;2(1):35.
Landis S, Murray T, Bolden S, Wingo P. Cancer statistics, 1998. CA: A Cancer Journal for Clinicians. 1998;48(1):6-29.
Schmid K. Lymph node and distant metastases of thyroid gland cancer. Metastases in the thyroid glands. Pathologe. 2015;36(S2):171-175
Parameswaran R, Shulin Hu J, Min En N, Tan W, Yuan N. Patterns of metastasis in follicular thyroid carcinoma and the difference between early and delayed presentation. The Annals of The Royal College of Surgeons of England. 2017;99(2):151-154.
Rajesh Kunadharaju P. New Treatment Options for Metastatic Thyroid Cancer [Internet]. PubMed Central (PMC). 2015 [cited 12 February 2020]. Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375431/
Treatment of Thyroid Cancer, by Type and Stage [Internet]. Cancer.org; 2019. [cited 9 January 2020] Available:https://www.cancer.org/cancer/thyroid-cancer/treating/by-stage.html
Cupisti K, Ramp U, Raffel A, Krausch M, Rehders A, Knoefel W. Multiple giant scalp metastases of a follicular thyroid carcinoma. World Journal of Surgical Oncology. 2008;6(1).
Durante C, Haddy N, Baudin E, Leboulleux S, Hartl D, Travagli J et al. Long-Term Outcome of 444 Patients with Distant Metastases from Papillary and Follicular Thyroid Carcinoma: Benefits and Limits of Radioiodine Therapy. The Journal of Clinical Endocrinology & Metabolism. 2006;91(8):2892-2899
Thyroid Cancer - Statistics [Internet]. Cancer.Net. 2019 [cited 7 January 2020] Available: https://www.cancer.net/cancer-types/thyroid-cancer/statistics
Abstract View: 42 times
PDF Download: 12 times