Factors Affecting Lung Cancer Survival: A Literature Review
Asian Oncology Research Journal,
Lung cancer is a disease which invades the lung tissue by formation of uncontrolled cell growth, and this may also affect the tissues near the lung. There are a wide range of prognostic factors which determine survival duration of lung cancer patients. Among the most important factors are patient demographics, disease factors and health care related factors. Lung cancer remains one of the leading causes of the overall cancer burden worldwide. The aim of this review is to investigate the existing knowledge and relevant literature on prognostic factors in lung cancer survival. Literature search was carried on OVID databases (1990-2011) that include Ovid MEDLINE in process and EMBASE. In Ovid, truncations were used. Only papers published in English were included. A total of 315 were found and refined, only 43 papers were reviewed. In conclusion, lung cancer survival is influenced by a number of factors that interact to determine the prognosis of patients. Lung cancer survival is not dependent on a single factor of these prognostics, but is affected by the interaction between them.
- Lung cancer
- prognostic factors.
How to Cite
Cancer Research UK. Lung cancer and smoking statistics - Key Facts; 2011.
Thun MJ, Hannan LM, Adams-Campbell LL, Boffetta P, Buring JE, Feskanich D, Flanders WD, Jee SH, Katanoda K, Kolonel LN, Lee IM, Marugame T, Palmer JR, Riboli E, Sobue T, Avila-Tang E, Wilkens LR, Samet JM. Lung cancer occurrence in never-smokers: an analysis of 13 cohorts and 22 cancer registry studies. PLoS Medicine/Public Library of Science. 2008;5(9): e185
Bray F, Sankila R, Ferlay J, Parkin DM. Estimates of cancer incidence and mortality in Europe in 1995. European Journal of Cancer. 2002;38(1):99-166.
Buccheri G, Ferrigno D. Prognostic factors in lung cancer: Tables and comments. European Respiratory Journal. 1994;7(7):1350-1364.
Chatkin JM, Abreu CM, Fritscher CC, Wagner MB, Pinto JA. Is there a gender difference in non-small cell lung cancer survival? Gender Medicine. 2004;1(1):41-7.
Hsu LH, Chu NM, Liu CC, Tsai SY, You DL, Ko JS. Sex-associated differences in non-small cell lung cancer in the new era: is gender an independent prognostic factor? Lung Cancer. 2009;66 (2):262-7.
Wisnivesky JP, Halm EA. Sex Differences in lung cancer survival: Do tumours behave differently in elderly women? J Clinical Oncology. 2007;13(25):1705-1711.
Ferguson MK, Skosey C, Hoffman PC, Golomb HM. Sex-associated differences in presentation and survival in patients with lung cancer, JCO. 1990;(8):1402-1407.
Schulte T, Schniewind B, Walter J, Dohrmann P, Chler T, Kurdow R. Age-related impairment of quality of life after lung resection for non-small cell lung cancer. Lung Cancer. 2010;68(1):115-20
Agarwal M, Brahmanday G, Chmielewski GW, Welsh RJ, Ravikrishnan KP. Age, tumor size, type of surgery and gender predict survival in early stage (stage I and II) non-small cell lung cancer after surgical resection. Lung Cancer. 2010;68(3):398-402.
Takigawa N, Segawa Y, Okahara M, Maeda Y, Takata I, Kataoka M, Fujii M. Prognostic factors for patients with advanced non-small cell lung cancer: Univariate and multivariate analyses including recursive partitioning and amalgamation. Lung Cancer. 1996;15(1):67-77.
Hurria A, Kris MG. Management of Lung Cancer in Older Adults. CA: A Cancer Journal for Clinicians. 2003;53(6):325-341.
Pallis AG, Gridelli C. Is age a negative prognostic factor for the treatment of advanced/metastatic non-small-cell lung cancer?. Cancer Treatment Reviews. 2010;36(5):436-41.
Pagano E, Filippini C, Di Cuonzo D, Ruffini E, Zanetti R, Rosso S, Bertetto O, Merletti F, Ciccone G. Factors affecting pattern of care and survival in a population-based cohort of non-small-cell lung cancer incident cases. Cancer Epidemiology. 2010;34(4):483-9.
Ou SH, Zell JA, Ziogas A, Anton-Culver H. Low socioeconomic status is a poor prognostic factor for survival in stage I nonsmall cell lung cancer and is independent of surgical treatment, race, and marital status. Cancer. 2008;112(9): 2011-20.
Yu XQ, O'Connell DL, Gibberd RW, Armstrong BK. Assessing the impact of socio-economic status on cancer survival in New South Wales, Australia 1996-2001. Cancer Causes & Control. 2008;19(10):1383-1390.
Potosky AL, Saxman S, Wallace RB, Lynch CF. Population variations in the initial treatment of non-small-cell lung cancer. J Clin Oncol. 2004;22(16):3261–3268.
Campbell NC, Elliott AM, Sharp L, Ritchie LD, Cassidy J, Little J. Rural factors and survival from cancer: analysis of Scottish cancer registrations. Br J Cancer. 2000;82:1863–1866.
Campbell NC, Elliott AM, Sharp L, Ritchie LD, Cassidy J, Little J. Impact of deprivation and rural residence on treatment of colorectal and lung cancer. British Journal of Cancer. 2002;87(6): 585-590 .
Hui AC, Vinod SK, Jalaludin BB, Yuile P, Delaney GP, Barton MB. Socio-economic status and patterns of care in lung cancer. Australian & New Zealand Journal of Public Health. 2005;29(4): 372-7
Tammemagi CM, Neslund-Dudas C, Simoff M, Kvale P. Impact of comorbidity on lung cancer survival. International Journal of Cancer. 2003;103(6):792-802
Asmis TR, Ding K, Seymour L, Shepherd FA, Leighl NB, Winton TL, Whitehead M, Spaans JN, Graham BC, Goss GD. National Cancer Institute of Canada Clinical Trials Group. Age and comorbidity as independent prognostic factors in the treatment of non small-cell lung cancer: a review of National Cancer Institute of Canada Clinical Trials Group trials. Journal of Clinical Oncology. 2008;26(1);54-9,
Regina GS, Dolores T, Jos G, Inma M, Jose M, Rafael R. Prognostic impact of comorbidity in elderly lung cancer patients: Use and comparison of two scores. Lung Cancer. 2010;72(1):108-13.
Dajczman E, Kasymjanova G, Kreisman H, Swinton N, Pepe C, Small D. Should patient-rated performance status affect treatment decisions in advanced lung cancer? Journal of Thoracic Oncology: Official Publication of the International Association for the Study of Lung Cancer. 2008;3(10):1133-1136
Blagden SP, Charman SC, Sharples LD, Magee LRA, Gilligan, D. Performance status score: do patients and their oncologists agree?, British Journal of Cancer . 2003;89:1022–1027.
Port JL, Kent MS, Korst RJ, Libby D, Pasmantier M, Altorki NK. Tumor size predicts survival within stage IA non-small cell lung cancer. Chest. 2003;124(5):1828-33,
Cangir AK, Kutlay H, Akal M, Gungor A, Ozdemir N, Akay H. Prognostic value of tumor size in non-small cell lung cancer larger than five centimeters in diameter. Erratum appears in Lung Cancer. 2005;50 (2):281-2. Lung Cancer. 2004;46(3):325-31.
Mery CM, Pappas AN, Burt BM, Bueno R, Linden PA, Sugarbaker DJ, Jaklitsch, M. Diameter of non-small cell lung cancer correlates with long-term survival. Implications for T stage. Chest. 2005;128: 3255-3260.
Lopez-Encuentra A, Duque-Medina JL, Rami-Porta R, Camara AG, Ferrando P. Staging in lung cancer: Is 3 cm a prognostic threshold in pathologic stage I non-small cell lung cancer? A multicenter study of 1020 patients. Chest. 2002;121:1515-1520
Yang F, Chen H, Xiang J, Zhang Y, Zhou J, Hu H, Zhang J, Luo X. Relationship between tumor size and disease stage in non-small cell lung cancer. BMC Cancer. 2010;10(1):474 .
Heyneman LE, Herndon JE, Goodman PC, Patz EF. Stage distribution in patients with a small (< 3 cm) primary nonsmall cell lung carcinoma. Cancer. 2001;92(12):3051-3055.
Al-Kattan K, Sepsas E, Townsend ER, Fountain SW. Factors affecting long term survival following resection for lung cancer. Thorax. 1996;51(12):1266-1269.
Nykamp V. Surgical treatment of non-small cell lung cancer. [Review] [9 refs]. South Dakota Medicine.The Journal of the South Dakota State Medical Association. 2010; 57-9.
Rudd R. Chemotherapy in the treatment of non-small cell lung cancer. Respiratory Disease in Practice. 1991;7:12-14.
Willard AF, Jerri LP, Herman RM. Ten-year survey of lung cancer treatment and Survival in Hospitals in the United States. Cancer. 1991;86:1867-1876.
Cartman ML, Hatfield AC, Muers MF, Peake MD, Haward RA, Forman D. Lung cancer: District active treatment rates affect survival. Journal of Epidemiology and Community Health. 2000;256(6):424-429 .
Fergusson R, McLean C, Dodds R, Gregor A. Palliative care of patients with lung cancer: Management practices and outcomes in South East Scotland. European Respiratory Journal. 1995;8 (SUPPL. 19)183S.
Auvinen A, Karjalainen S. Possible explanations for social class differences in cancer patient survival. IARC Scientific Publications. 1997;(138):377-97.
Yim J, Hwang S, Yoo K, Kim C. Contribution of income-related inequality and healthcare utilisation to survival in cancers of the lung, liver, stomach and colon. Journal Epidemiol Community Health; 2010.
Chen Z, King W, Pearcey R, Kerba M, Mackillop WJ. The relationship between waiting time for radiotherapy and clinical outcomes: A systematic review of the literature. Radiotherapy and Oncology. 2008;87(1):3-16.
Ernstmann N, Neumann M, Ommen O, Galushko M, Wirtz M, Voltz R, Hallek M, Pfaff H. Determinants and implications of cancer patients' psychosocial needs. Supportive Care in Cancer. 2009;17(11): 1417-23.
Abstract View: 2178 times
PDF Download: 1031 times