Asian Oncology Research Journal 2020-04-04T12:04:28+00:00 Asian Oncology Research Journal Open Journal Systems <p style="text-align: justify;"><strong>Asian Oncology Research Journal</strong>&nbsp;aims to publish&nbsp;high-quality&nbsp;papers (<a href="/index.php/AORJ/general-guideline-for-authors">Click here for Types of paper</a>) in all areas of&nbsp;‘Cancer, Tumor&nbsp;and&nbsp;Oncology&nbsp;research’. This journal facilitates the research and wishes to publish papers as long as they are technically correct, scientifically motivated. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer-reviewed, open access INTERNATIONAL journal.</p> <p style="text-align: justify;"><img src="/public/site/images/sciencedomain/free-sign.gif" width="80" height="32"></p> <p style="text-align: justify;"><strong>Publication Charge: FREE</strong>. All the manuscripts submitted within this month will be published free of cost. There is no publication charge for this month.&nbsp;</p> Laboratory Assessment of Gastrointestinal Cancer Patients Pre and Post Chemotherapy 2020-03-25T04:54:39+00:00 Rajini Kurup Latoya Gooding Cecil Boston Shane Blair Niromanie Ramsarup Yeama Singh <p><strong>Aims: </strong>Chemotherapy-induced neutropenia is a common side effect in cancer patients. Other hematopoietic lineages are also decreased in cancer patient. Altered laboratory parameters would prevent patients from chemotherapy. Thus this study identified the significance of blood parameters during chemotherapy among Gastrointestinal (GI) cancer patients.</p> <p><strong>Study Design:</strong> Laboratory based descriptive study.</p> <p><strong>Place and Duration of Study:</strong> Cancer Institute, Georgetown Public Hospital Cooperation, Guyana between 2011 to 2015.</p> <p><strong>Methodology:</strong> A total of 47 patients were included in the study who were diagnosed with GI cancer. Mean±SD was used to measure biochemical and hematological means.</p> <p><strong>Results:</strong> Mean of the patients age was 59.9. Most prevalent GI cancer was of colon (44.7), followed by rectum (12.8). Cancer of maxilla, oesophagus, gall bladder, liver and rectum all had almost the same prevalence (2.1). Most patients used Fluorouracil (74.5%) and Oxaliplatin (72.3). And 42.6% of the patients underwent radiation. There was a variation noted in the values of the hematological and biochemical parameters.</p> <p><strong>Conclusion:</strong> The cancer patients showed a huge variations in the biochemical and hematological parameters.</p> 2020-03-25T00:00:00+00:00 ##submission.copyrightStatement## Retrospective Clinico-epidemiological Study of Endometrial Carcinoma, Mansoura Experience 2020-03-25T12:27:35+00:00 Fatma M. Elissawy Amal A. F. Halim Rasha M. Abdel-Latif Abdel-Monaem M. Nour-Elden Amany Hassan <p><strong>Aims: </strong>Determining epidemiological characteristics and treatment outcome of endometrial carcinoma (EC) patients treated at Clinical Oncology and Nuclear Medicine Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt from Jan 2000 to Dec 2013 inclusive.</p> <p><strong>Study Design: </strong>Retrospective study.</p> <p><strong>Place and Duration of Study:</strong> Clinical Oncology and Nuclear Medicine Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt.</p> <p><strong>Methodology:</strong> Clinical data of 226 EC patients were retrospectively abstracted from the records. Data collected included presenting symptoms, detailed examination and investigations, the treatment protocol, and the outcome.</p> <p><strong>Results:</strong> Post-menopausal females were 183 (81%). The incidence of disease was 75.7% among cases with BMI 30-39.9. Forty-two (18.6%) were diagnosed with positive family history. Postmenopausal bleeding was the most common presenting symptom (79.6%). Endometrioid adenocarcinoma was the most common pathology (85.4%) and 48 (21.2%) were diagnosed as grade III.Eighty-four (37.2%) were stage IB and 62 (27.4%) were stage 1A.EC was classified into Low-risk cases (FIGO 2009 stage IA, grade 1 or 2, of endometrioid type histology, intermediate-risk cases ( stage IA grade 3 endometrioid EC&amp;IB grade 1,2 ) and high-risk cases( FIGO stage IB of grade 3 or non-endometrioid histology, stage II, and any stage with non-endometrioid histology). Most of our patients were intermediate risk [95 patients (42.1%)] followed by high risk [81 patients (35.8%)]. Adjuvant treatment was received by 183 patients (90% of whom were intermediate and high risk). Combined EBRT plus brachytherapy was not given to low-risk patients. The 5- year DFS &amp; OS were 46.4% &amp; 65.1% respectively.BMI, ECOG, tumour grade, staging, using EBRT plus VBT and using combined chemotherapy and radiotherapy were the significant prognostic factors.</p> <p><strong>Conclusion:</strong> The majority of our EC cases were obese post-menopausal women having early stages and intermediate-risk disease. Serious investigation of postmenopausal bleeding is a must and tailoring the therapy of EC based on the risk category is worthy.</p> 2020-03-25T00:00:00+00:00 ##submission.copyrightStatement## Prevalence and Risk Factors for Breast Cancer: A Hospital Based Cross-sectional Study in Nepal 2020-04-03T06:43:48+00:00 Pramodh Chaudhary Sanjaya Regmi Ashok Pandey <p><strong>Aims:</strong>&nbsp;The aims of this study were to assess risk factors of breast cancer in female and to find out the hospital-based prevalence of female breast cancer in Nepal.</p> <p><strong>Study Design: </strong>Hospital-based descriptive cross-sectional study was done.</p> <p><strong>Place and Duration of Study:</strong>&nbsp;The study sites were Bhaktapur Cancer hospital, Nepal. The duration of the study was 12 months.</p> <p><strong>Methodology</strong><strong>:</strong>&nbsp;A hospital-based descriptive cross-sectional study was done to assess risk factors and prevalence of Breast cancer in Nepal at Bhaktapur Cancer Hospital. Data was collected by simple random sampling method and hospital record was collected to assess the prevalence of breast cancer and data analysis were carried out using SPSS software.</p> <p><strong>Results:</strong> The study shows the increase of the age; increases the risk of breast cancer. The mean age group is 52.65 with a standard deviation of 9.518. Out of 83 participants, 42 (48.2%) was a smoker and 46 (55.4%) were alcoholics. 15 (18.1%) of the participants have early menarche before the age of 7-11 years. As of 2013 and 2012 hospital data shows that breast cancer is third prevalent among all types of cancer. In 2013 Female breast cancer was 171 among all cancer 1713 and in 2012, 155 among 1602 of all cancer.</p> <p><strong>Conclusion:</strong> Breast cancer is the most common cancer. The strongest risk factor for breast cancer is age; the increase of age increases the risk of breast cancer.</p> 2020-04-03T00:00:00+00:00 ##submission.copyrightStatement## Effectivity of Some Natural Compounds against Ehrlich Tumor and Associated Diseases 2020-04-04T12:04:28+00:00 Thulfiqar Fawwaz Mutar Ehab Tousson <p>Ehrlich model is mammary cancer it is passed via intraperitoneal passages from a mouse to another. Because of the ability of Ehrlich tumor to grow and spread rapidly after transplantation, it has been used in many experimental studies looking for a way to fight diseases and reduce its risk. The Ehrlich solid tumor (EST), derived from the mouse breast adenocarcinoma which is an aggressive and fast growing carcinoma able to develop both in the ascitic (EAC) or in the solid form depending whether inoculated intraperitoneously or subcutaneously, respectively. Plants and their products have a variety of biological activities that include anti-tumor, anti-inflammation, and antioxidant activities. However, natural products have inspired many researchers who have recommended the use of natural resources to prevent some tumors and chronic diseases.</p> 2020-04-04T00:00:00+00:00 ##submission.copyrightStatement##